Author: Nabeel Syed
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Cirrhosis
Definition Annu Rev Pharmacol Toxicol 2005;45:605-28 Lancet 2008;371:838-51 Acute liver injury leads to complex inflammatory reactions and matrix remodeling processes which result in the restoration of normal architecture Chronic liver injury leads to prolonged and dysregulated healing with accumulation of matrix proteins which ultimately progresses to cirrhosis Cirrhosis is an advanced stage of liver fibrosis…